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Clinical Trial Results One-Pager

Report a trial's results: endpoints, response and safety. Research teams use it for readouts.

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What’s on It

  • Headline numbersThe Primary Endpoint
  • Line chart over timeResponse Over Time
  • Key pointsWhat the Data Says
  • Before and after chartSecondary Endpoints, Baseline to Week 16

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Phase II Readout: RVX-311
Moderate-to-severe eczema · 312 patients · 16 weeks
The Primary Endpoint
EASI-75 at week 16
68%
+29 pts
vs 39% on placebo
Primary endpoint
p<0.001
Powered at 90%
Patients randomised
312
3 arms, 24 sites
Discontinued
4.1%
-2.3 pts
vs 6.4% on placebo
Response Over Time
02550751006839W2W4W8W12W16
RVX-311 300mgPlacebo
What the Data Says
Separation from placebo is clear by week 4 and widens to week 16.
No serious adverse events attributed to study drug.
Effect holds in the 94 patients who failed a biologic before.
Secondary Endpoints, Baseline to Week 16
BaselineWeek 16
Peak itch (NRS)2.6 score-4.8
Sleep loss (NRS)2.2 score-3.9
Quality of life (DLQI)4.9 score-9.9
Affected body area (%)12 score-29
The compound cleared its primary endpoint with room to spare. The decision in front of the board is Phase III design, not whether to continue.

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